Objective:
Congressionally mandated grant funds are used to support research at NCAUR and University of Illinois to develop technologically more efficient bioproduction systems capable of producing a greater diversity of useful products. Programs focus on cellular and subcellular biology, immobilization technology, separation and harvesting technologies and sensors, process control, and rapid screening technologies.

Approach:
Such systems an anaerobic, mixed culture, and continuous fermentation and fluidized beds of immobilized enzymes will be investigated in search of advances in bioprocessing efficiency and novel bioconversions. Diverse microbes and enzymes there from will be investigated for their usefulness in these systems, as will innovative sensors and process controls and separation and harvesting methods. 11/92 changed agreement # from 59-32U4- 7-119; Start/Term Dates 9/15/87 9/14/92; Award Date 1/16/91; and PI investigator from K.D.Murrell to R.L.Dunkle. 2/98 continued agreement # 59- 3K95-3-126; Start/Term Dates changed from 10/01/92 09/30/97; Award Date 10/22/92; PI investigator remains R.Dunkle. Agmt # changed to 59-3601-8- 303; Start/Term Dates 10/01/97 09/30/02; Award Date 02/10/98; PI A.D. Hewings. New AD-416/417 replacing 0500-00035-003-01G.