Project Number: 1235-51520-037-03
Project Type: Nonfunded Cooperative Agreement

Start Date: Jan 01, 2004
End Date: Dec 31, 2008

Objective:
The objective of this cooperative research project is to encourage a program of collaboration between contracting parties to further develop teaching and research activities that relate to oxidative stress and insulin activity.

Approach:
In order to achieve the goals outlined in this cooperative agreement, both parties will share resources throughout the exchange of students (PhD or post PhD), research visits to cooperation institutions, participation in seminars, academic meetings, and thesis juries, and the exchange of academic materials and scientific publications. The project will focus on using cell culture, animals, and humans to demonstrate the beneficial effects of chromium, cinnamon, and tea extracts as they relate to oxidative stress and insulin action. The mechanisms of these possible antioxidants and insulin sensitizers will be investigated. In addition, the nutritional chromium status of European elderly will be evaluated as well as the genotoxicity of chromium forms in animals and cells.