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Research Project:
CHARACTERIZATION OF OLFACTORY PROTEINS OF THE YELLOW FEVER MOSQUITO AEDES AEGYPTI AS TARGETS FOR THE STUDY OF CHEMOSENSORY DETERRENTS
Location: Invasive Insect Biocontrol and Behavior Laboratory
Project Number: 1275-32000-001-13
Project Type:
Specific Cooperative Agreement
Start Date: Sep 04, 2007
End Date: Sep 30, 2009
Objective:
To characterize and develop the SNMPs of Ae. aegypti as molecular targets for the disruption of chemosensory based behaviors in the mosquito Ae. aegypti.
Approach:
The goal of this project is to develop chemically based strategies that disrupt chemosensory mediated mosquito behavior; these strategies should dramatically reduce mosquito-human interaction and be safe for use around humans and non-mosquito animals. To accomplish this goal, biochemical processes must be identified that are (1) accessible to chemical treatment, (2) are appropriately unique to the target species, and (3) are sufficiently centrally localized such that their disruption will maximally distress the target species. This project focuses on the characterization of a mosquito chemosensory protein called SNMP (Sensory Neuron Membrane Protein), and the development of methodologies that will disrupt SNMP function.
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Last Modified: 11/07/2008
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