A new technique speeds analysis of the composition of solutions by coupling capillary electrophoresis (CE) with fluorescence correlation spectroscopy (FCS). The CE/FCS technique, developed at Los Alamos National Laboratory, capitalizes on the selectivity of the CE separation technique and the sensitivity and rapid analysis times of the FCS optical technique to quickly identify small molecules in very dilute solutions. This work is reported in Analytical Chemistry 70(21):4463-4471. The rapid analysis possible with the CE/FCS technique will have many applications in the analytical chemistry field, particularly for bioscience-related analyses. This work is supported by the Office of Biological and Environmental Research. Contact: Richard Keller, Los Alamos National Laboratory, (505) 667-3018, keller@lanl.gov
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